Brendan Rodgers has named the duo, who each missed much of last season through injury, in his XI for the friendly encounter with the Italian outfit at the iconic venue in the United States.
Fabio Borini and youngster Jordon Ibe support Rickie Lambert in attack, while centre-back Martin Skrtel again takes the captain's armband.
The match will be broadcast live online for LFCTV GO subscribers, with kick-off at 7.30pm local time and 12.30am BST. Click here for more information on watching the game.
Liverpool XI in full: Jones, Kelly, Skrtel, Coates, Enrique, Lucas, Allen, Coutinho, Borini, Lambert, Ibe.
Substitutes: Ward, Agger, Henderson, Can, Suso, Coady, Phillips, Robinson, Peterson.